We Develop Pan Coronavirus Antivirals

A new Covid sub-variant is causing some concern in the US, where it is spreading rapidly.

Some cases have also been recorded in the UK, so what do you need to know about XBB.1.5?

About 40% of confirmed U.S. Covid cases are caused by the XBB.1.5 strain, up from 20% a week ago.

What was it like to keep research work going during the worst of the pandemic? And how close are we to a vaccine that works against all current and future coronavirus variants?

Investigators at the University of Bristol and Biognos AB have identified a structural feature that distinguished the deadly coronavirus strains from harmless, common cold-causing variants. The findings, which were published in the Nov. 23, 2022

Scientists have discovered that a tailor-made pocket within the SARS-CoV-2 spike protein, which is capable of binding itself to the human cell surface, is what results in some coronaviruses causing severe disease.

The free fatty acid–binding pocket is a conserved hallmark in pathogenic β-coronavirus spike proteins from SARS-CoV to Omicron

Halo Winner at OBN Awards 2022 !

Survey indicates that getting reinfected worsens symptoms of Long COVID or triggers a recurrence of symptoms in people who have recovered.

Descendants of Omicron are proliferating worldwide — and the same mutations are coming up again and again.
Some call it a swarm of variants — others refer to it as variant soup. Whatever it’s called, the current crop of immunity-dodging offshoots of the Omicron variant of SARS-CoV-2 is unprecedented in its diversity. This complexity makes it harder to predict coming waves of infection. It might even lead to a ‘double wave’ in some places, as first one variant and then another overtakes a population.

The OBN Awards, now in their 14th year, are a highly regarded and sought-after awards programme for the Life Sciences industry, designed to celebrate innovation and outstanding achievement across all corners of the life sciences industry.

As long as humans inhabit the earth, viruses will be part of life, and learning how to defend against novel coronaviruses will be vital for global health.

The surface proteins found on
both pathogens and host cells mediate cell
entry (and exit) and influence disease progression and transmission. Both types of proteins can bear host-generated posttranslational

There is a mixture of variants in circulation, and signs of vaccine fatigue in the population.
After two winters of Covid anguish, one would be forgiven for viewing the shortening of days with a sense of trepidation. It would not be entirely misplaced.

New WHO/Europe strategy urges countries to urgently address gaps in pandemic monitoring and response to avoid preventable deaths and severe disruptions to health systems

Imre Berger, Professor of Biochemistry and Chemistry and Director of Bristol’s Max Planck Centre for Minimal Biology has been elected as a Fellow of the Academy of Medical Sciences for his outstanding contributions to biomedical science and notable discoveries during the COVID-19 pandemic.

Experts fear condition will hit people’s ability to work and have costs for employers and government, Jane Dalton writes

The U.S. Food and Drug Administration is continually monitoring how authorized and approved treatments for COVID-19 are affected by changing variants

A resurgence of Covid cases is under way across the UK, with infections in the over-70s at a record high and school leaders fearing that preparations

The latest coronavirus news updated every day including coronavirus cases, the latest news, features and interviews

COVID-19 can cause the brain to shrink and damage areas linked to memory and smell, says a new study by Oxford University that was published in the Nature journal

People suffering from COVID-19 could have several different SARS-CoV-2 variants hidden away from the immune system in different parts of the body, finds new research published in Nature Communications by an international research team. The study’s authors say that this may make complete clearance of the virus from the body of an infected person, by their own antibodies, or by therapeutic antibody treatments, much more difficult.

Halo CTO Professor Christiane Schaffitzel discovered the SARS-CoV-2 Achilles’ heel targeted by Halo’s safe, self-administered antiviral treatments and prophylactics

A future variant of Covid-19 could be much more dangerous and cause far higher numbers of deaths and cases of serious illness than Omicron, leading UK scientists have warned.

However, the number of deaths remains well below levels in previous waves of the virus.

As the global burden of SARS-CoV-2 infections escalates, so does the evolution of viral variants with increased transmissibility and pathology. In addition to this entrenched diversity, RNA viruses can also display genetic diversity within single infected hosts with co-existing viral variants evolving differently in distinct cell types.

A new study has shown how SARS-CoV-2 may contribute to severe microvascular damage seen in severely-ill COVID-19 patients by transforming human heart vascular cells into inflammatory cells, without infecting them.

The emergence of the highly transmissible B.1.1.529 Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is concerning for antibody countermeasure efficacy because of the number of mutations in the spike protein.

Even during the strange time warp that has been the COVID-19 pandemic, opening a new calendar to a clean page headed “January” stirs the hopeful possibility of fresh starts and exciting changes.

Registered nurse Giyun Kim, left, works with patient Marcus Miller in the COVID unit at Providence Little Company of Mary Medical Center in Torrance on Jan. 11.(Francine Orr / Los Angeles Times)