We Develop Pan Coronavirus Antivirals

Even during the strange time warp that has been the COVID-19 pandemic, opening a new calendar to a clean page headed “January” stirs the hopeful possibility of fresh starts and exciting changes.

Registered nurse Giyun Kim, left, works with patient Marcus Miller in the COVID unit at Providence Little Company of Mary Medical Center in Torrance on Jan. 11.(Francine Orr / Los Angeles Times)

New data covers the first wave of the coronavirus pandemic in England and is thought to be one of the largest analyses of care home residents.

A third of patients with the most common type of leukaemia fail to generate any measurable antibody response following two doses of COVID-19 vaccination.

Nearly all of the monoclonal antibodies used to prevent severe disease fail to stand up to the new variant, laboratory assays show.

A team of Bristol scientists have made an astonishing discovery; a feature of the coronavirus, and its variants, perfect for placing an antiviral molecule that could slash Covid infections.

Druggable pocket and Halo’s antiviral mechanism fully conserved in all Variants of Concern – including Omicron !

The omicron variant of Covid-19 is “probably the most significant threat we’ve had since the start of the pandemic” and could place

Most pessimistic scenarios could see between 25,000 and 75,000 deaths over next five months without action

Professor John Edmunds said he would be very surprised if updated vaccines to tackle variants were not needed.

Sir Jeremy Farrar, director of Wellcome Trust, suggests emergence of Omicron variant means pandemic is far from over

Government policy and the rate of immunity will determine how quickly coronavirus settles into a ‘predictable endemic state’, advisers say

At least 17 people suspected of having the Omicron variant of coronavirus after a ‘super spreader’ Christmas party in Oslo were fully vaccinated, city health officials have said.

More than 100 cases of new variant have now been found in England; Strict social distancing will be required in Ireland’s bars and restaurants with mandatory table service and a maximum of six people per table.

As of this morning, British drug regulators have approved the Covid-19 antiviral drug molnupiravir for use in Covid-19 patients at risk for severe illness, making them the first public health officials to do so.

Scientists from the University of Bristol and start-up Halo Therapeutics are developing antiviral treatments that could prevent the virus from entering the body.The team recently reported a breakthrough discovery in Science magazine. They found that exposing SARS-CoV-2 to linoleic acid locks the virus’s spike protein into a closed shape. This:  blocks the virus’s entry into cells slows down its replication inside cells prevents it spreading and infecting people. The research was part-funded by the Biotechnology and Biological Sciences Council (BBSRC). A ‘pan corona’ treatment The team’s spinout company, Halo Therapeutics, was formed to take the research to clinical trials as soon as possible.Treatments under development include a nasal spray, soon to be followed by an inhaler. They work by preventing the virus penetrating cells in the:  nose throat lungs. Laboratory studies indicate that the antiviral will work against all strains, including the highly contagious Kent, South African and Brazilian variants. At home antiviral treatment Professor Imre Berger, director of the Max Planck-Bristol Centre for Minimal Biology at Bristol and Halo’s chief executive said: The aim of our treatment is to significantly reduce the amount of virus that enters the body and to stop it from multiplying. Then, even if people

Taking the long view fighting COVID-19 While the world has been focused on a vaccine, Professor Imre Berger is taking the long view on coronavirus, by exploring how best to treat the virus as an ongoing problem

It’s an attractive prospect: a single pill, popped immediately after you test positive for Covid, to stop the virus in its tracks and prevent serious disease.

Since the novel SARS-CoV-2 coronavirus changed everyone’s lives in March 2020, an extraordinary amount of time and effort has gone into understanding and characterizing this virus.

While the world has been focused on a vaccine, Professor Imre Berger is taking the long view on coronavirus, by exploring how best to treat the virus as an ongoing problem, including targeting ‘hot zones’.

A team of top scientists from the University of Bristol have announced the formation of a new biotech company that is developing newly patented potential treatments for Coronavirus.

A team of top scientists from the University of Bristol have announced the formation of a new biotech company that is developing ground-breaking and newly patented potential treatments for Coronavirus.

A team of top scientists from the University of Bristol have announced the formation of a new biotech company that is developing ground-breaking and newly patented potential treatments for coronavirus.

A team of top scientists from the University of Bristol have announced the formation of a new biotech company that is developing ground-breaking and newly patented potential treatments for coronavirus.

Based on a study of a British biotech company, they discovered a molecule that transforms the shape of the COVID-19 virus’s spike protein. The shift can prevent it from penetrating human cells.

Clinical trials will shortly be launched into pivotal, cost-effective antiviral treatments for COVID-19 following the discovery of a molecule which changes the shape of the SARS-CoV-2 spike protein and in so doing inhibits the virus’ ability to enter cells.

A British biotech company is moving towards Phase II clinical trials of a range of treatments to tackle coronavirus infections.

A team of top scientists from the University of Bristol have announced the formation of a new biotech company that is developing ground-breaking and newly patented potential treatments for coronavirus.

A team of scientists from the University of Bristol have announced the formation of a new BioTech company developing ground-breaking and newly patented potential treatments for COVID-19.

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